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On June 13, 2019 we lost our colleague Edvards Liepiņš, an outstanding scientist, NMR spectroscopist, teacher and mentor. The journal Chemistry of Heterocyclic Compounds has published our In Memoriam in his honour.
In preparation for the celebration of Latvia’s 100th anniversary on 18th November 2018, the national TV was interviewing young scientists, who have returned to Latvia after spending several years abroad, among them, our group leader Kristaps Jaudzems.
On February 16, 2018 the Latvian Academy of Sciences (LZA) and the Science Foundation held the award ceremony of the most significant science achievements in Latvia in 2017. One of the prizes was awarded to Kristaps Jaudzems and Martins Otikovs for “Determination of the molecular mechanism of spider silk formation and assessment of the degree of biomimicry of artificial spider silk spinning”.
|Kristaps Jaudzems receives the diploma from Inese Čakstiņa.||All award winners.|
Photos by Jānis Brencis.
Latvian Academy of Sciences has announced 12 most important achievements of 2017 in Latvian science. Among them is our study on the determination of the molecular mechanism of spider silk formation and assessment of the degree of biomimicry of artificial spider silk spinning, which was carried out in collaboration with Karolinska Institute in Sweden (Karolinska Institutet) and Institute of Analytical Sciences in France (Institut des Sciences Analytiques).
Spider silk is a high-performance material with perspective applications in a range of areas from biomedicine to construction. The spiders spin their web from silk fibres that are made of proteins. Thus far, the process of the spider silk fibre formation was incompletely understood, making it difficult to develop effective technologies for the production of artificial spider silk. Researchers at LIOS have studied the process of native spider silk spinning and established the mechanism of molecular transformations that ensure controlled conversion of soluble silk proteins into solid fibres. The acquired knowledge was used to assess the degree of biomimicry of state-of-the-art approaches for artificial spider silk spinning, allowing to propose improved technologies for the production artificial spider silk.
The achievement was featured in the newspaper Latvijas Avīze, as well as on national TV (LTV Rīta Panorāma) and on skaties.lv.
|in collaboration with Centre de RMN à Très Hauts Champs de Lyon Lecturers:
Dr. Guido Pintacuda
Dr. Sachin Chaudhari
Dr. Jan Stanek
Dr. Diane Cala
11th-14th July 2016, Latvian Institute of Organic Synthesis
|Monday, 11th July||Practicals at the spectrometer|
|10-12||Practical on spectrometer setup (all lecturers)|
|13-17||Practical on experiment setup (all lecturers)|
|Tuesday, 12th July||Lectures for general audience|
|9:15-10:30||Solid state NMR principles, applications in chemistry and biology (Guido Pintacuda)|
|10.45-12.00||Solid state NMR of materials (Sachin Chaudhari)|
|12.45-13.30||Successful writing of ERC grant application (Guido Pintacuda)|
|Wednesday, 13th July||Lectures for expert audience|
|10-12||Protein sample preparation for solid state NMR (Diane Cala)|
|13-15||Solid state NMR of proteins (Guido Pintacuda and Jan Stanek)|
|Thursday, 14th July||Practicals on data processing and analysis|
|10-12||Processing of NMR spectra (all lecturers)|
|13-17||Analysis of protein solid state NMR spectra (all lecturers)|
22nd September 2015, Conference Hall, Latvian Institute of Organic Synthesis
|9.45-10.00||Registration and coffee|
|10.05-10.50||NMR studies of protein ligand interactions|
|10.50-11.35||Structure based drug design|
|12.00-12.45||Isotope labeling of proteins by expression in E.coli|
|12.45-13.15||Discussions and snacks|